doi:10.3969/j.issn.1673-8640.2024.08.014

Abstract

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R446.1

Figures/Tables 8

References 35

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作者	发表年	研究类型	研究中心	研究地点	金标准	研究例数/例	流行率/%	TP/例	FP/例	FN/例	TN/例	曲线下面积	截断值	敏感性	特异性
CROUSER^[4]	2017年	前瞻	多	急诊	2.0	1 320	7.4	75	330	23	892	0.790	20.5	0.77	0.73
CROUSER^[5]	2019年	前瞻	多	急诊	2.0	2 158	17.8	285	496	100	1 277	0.790	20.0	0.74	0.72
AGNELLO^[6]	2020年	回顾	单	急诊	2.0	2 215	4.0	81	151	7	1 976	0.964	23.5	0.92	0.93
POLILLI^[7]	2020年	前瞻	单	病房	3.0	260	40.4	99	47	6	108	0.870	21.9	0.94	0.70
AGNELLO^[8]	2021年	回顾	单	急诊	2.0	703	6.8	38	105	10	550	0.876	23.0	0.79	0.84
HAUSFATER^[9]	2021年	前瞻	多	急诊	3.0	1 517	9.5	117	426	27	947	0.820	21.5	0.81	0.69
HOU^[10]	2021年	回顾	单	急诊	2.0	1 480	20.0	191	469	105	715	0.625	22.1	0.65	0.60
PIVA^[11]	2021年	前瞻	单	急诊	3.0	506	22.1	75	88	37	306	0.785	24.6	0.67	0.78
POLILLI^[12]	2021年	前瞻	单	ICU	3.0	129	57.4	56	6	18	49	0.840	23.0	0.75	0.89
WOO^[13]	2021年	前瞻	单	急诊	3.0	549	34.2	156	181	32	180	0.710	19.8	0.83	0.50
JO^[14]	2022年	回顾	单	急诊	3.0	1 404	37.0	385	407	135	477	0.670	21.7	0.74	0.54
LI^[15]	2022年	前瞻	单	急诊	3.0	402	13.4	38	113	16	235	0.722	23.4	0.70	0.68
MALINOVSKA^[16]	2022年	前瞻	单	急诊	3.0	7 952	2.3	140	2 577	40	5 195	0.800	20.0	0.78	0.67
OGNIBENE^[17]	2022年	未知	单	急诊	3.0	308	24.7	71	135	5	97	0.770	20.0	0.93	0.42
POLILLI^[18]	2022年	前瞻	单	急诊	2.0	2 724	10.0	200	429	72	2 023	0.842	22.0	0.74	0.83
POZ^[19]	2022年	前瞻	单	急诊	2.0	985	6.4	55	261	8	661	0.849	20.1	0.87	0.72
YU^[20]	2022年	回顾	单	急诊	3.0	1 234	6.6	69	196	13	956	0.896	21.9	0.84	0.83
CUSINATO^[21]	2023年	回顾	单	急诊	3.0	2 570	21.7	426	1 315	132	697	0.590	20.0	0.76	0.35
LIN^[22]	2023年	前瞻	单	急诊	2.0	2 610	20.0	400	764	122	1 324	0.766	20.0	0.77	0.63

作者	发表年	研究类型	研究中心	研究地点	金标准	研究例数/例	流行率/%	TP/例	FP/例	FN/例	TN/例	曲线下面积	截断值	敏感性	特异性
CROUSER^[4]	2017年	前瞻	多	急诊	2.0	1 320	7.4	75	330	23	892	0.790	20.5	0.77	0.73
CROUSER^[5]	2019年	前瞻	多	急诊	2.0	2 158	17.8	285	496	100	1 277	0.790	20.0	0.74	0.72
AGNELLO^[6]	2020年	回顾	单	急诊	2.0	2 215	4.0	81	151	7	1 976	0.964	23.5	0.92	0.93
POLILLI^[7]	2020年	前瞻	单	病房	3.0	260	40.4	99	47	6	108	0.870	21.9	0.94	0.70
AGNELLO^[8]	2021年	回顾	单	急诊	2.0	703	6.8	38	105	10	550	0.876	23.0	0.79	0.84
HAUSFATER^[9]	2021年	前瞻	多	急诊	3.0	1 517	9.5	117	426	27	947	0.820	21.5	0.81	0.69
HOU^[10]	2021年	回顾	单	急诊	2.0	1 480	20.0	191	469	105	715	0.625	22.1	0.65	0.60
PIVA^[11]	2021年	前瞻	单	急诊	3.0	506	22.1	75	88	37	306	0.785	24.6	0.67	0.78
POLILLI^[12]	2021年	前瞻	单	ICU	3.0	129	57.4	56	6	18	49	0.840	23.0	0.75	0.89
WOO^[13]	2021年	前瞻	单	急诊	3.0	549	34.2	156	181	32	180	0.710	19.8	0.83	0.50
JO^[14]	2022年	回顾	单	急诊	3.0	1 404	37.0	385	407	135	477	0.670	21.7	0.74	0.54
LI^[15]	2022年	前瞻	单	急诊	3.0	402	13.4	38	113	16	235	0.722	23.4	0.70	0.68
MALINOVSKA^[16]	2022年	前瞻	单	急诊	3.0	7 952	2.3	140	2 577	40	5 195	0.800	20.0	0.78	0.67
OGNIBENE^[17]	2022年	未知	单	急诊	3.0	308	24.7	71	135	5	97	0.770	20.0	0.93	0.42
POLILLI^[18]	2022年	前瞻	单	急诊	2.0	2 724	10.0	200	429	72	2 023	0.842	22.0	0.74	0.83
POZ^[19]	2022年	前瞻	单	急诊	2.0	985	6.4	55	261	8	661	0.849	20.1	0.87	0.72
YU^[20]	2022年	回顾	单	急诊	3.0	1 234	6.6	69	196	13	956	0.896	21.9	0.84	0.83
CUSINATO^[21]	2023年	回顾	单	急诊	3.0	2 570	21.7	426	1 315	132	697	0.590	20.0	0.76	0.35
LIN^[22]	2023年	前瞻	单	急诊	2.0	2 610	20.0	400	764	122	1 324	0.766	20.0	0.77	0.63

亚组	研究数/项	敏感性（95%CI）	P值	特异性（95%CI）	P值
研究类型
前瞻	12	0.79（0.74~0.84）	<0.01	0.72（0.63~0.81）	0.23
回顾/不清楚	7	0.84（0.75~0.87）	<0.01	0.68（0.56~0.81）	0.23
研究中心
多中心	3	0.77（0.67~0.88）	<0.01	0.71（0.54~0.89）	0.37
单中心	16	0.80（0.76~0.84）	<0.01	0.70（0.63~0.78）	0.37
诊断标准
sepsis 3.0	11	0.81（0.76~0.86）	<0.01	0.65（0.56~0.75）	<0.01
sepsis 2.0	8	0.78（0.72~0.84）	<0.01	0.77（0.68~0.85）	<0.01
阳性病例数（n）
≥100	11	0.77（0.72~0.82）	<0.01	0.64（0.55~0.74）	<0.01
<100	8	0.83（0.78~0.89）	<0.01	0.78（0.70~0.86）	<0.01
截断值
≥22	7	0.75（0.68~0.82）	<0.01	0.81（0.74~0.88）	0.72
<22	12	0.82（0.78~0.86）	<0.01	0.63（0.55~0.72）	0.72
研究地点
急诊	17	0.79（0.75~0.83）	<0.01	0.69（0.62~0.77）	0.12
ICU/病房	2	0.87（0.78~0.96）	<0.01	0.81（0.63~0.98）	0.12

亚组	研究数/项	敏感性（95%CI）	P值	特异性（95%CI）	P值
研究类型
前瞻	12	0.79（0.74~0.84）	<0.01	0.72（0.63~0.81）	0.23
回顾/不清楚	7	0.84（0.75~0.87）	<0.01	0.68（0.56~0.81）	0.23
研究中心
多中心	3	0.77（0.67~0.88）	<0.01	0.71（0.54~0.89）	0.37
单中心	16	0.80（0.76~0.84）	<0.01	0.70（0.63~0.78）	0.37
诊断标准
sepsis 3.0	11	0.81（0.76~0.86）	<0.01	0.65（0.56~0.75）	<0.01
sepsis 2.0	8	0.78（0.72~0.84）	<0.01	0.77（0.68~0.85）	<0.01
阳性病例数（n）
≥100	11	0.77（0.72~0.82）	<0.01	0.64（0.55~0.74）	<0.01
<100	8	0.83（0.78~0.89）	<0.01	0.78（0.70~0.86）	<0.01
截断值
≥22	7	0.75（0.68~0.82）	<0.01	0.81（0.74~0.88）	0.72
<22	12	0.82（0.78~0.86）	<0.01	0.63（0.55~0.72）	0.72
研究地点
急诊	17	0.79（0.75~0.83）	<0.01	0.69（0.62~0.77）	0.12
ICU/病房	2	0.87（0.78~0.96）	<0.01	0.81（0.63~0.98）	0.12

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