Study on the serology identification of para-Bombay phenotype and the investigation of a family

doi:10.3969/j.issn.1673-8640.2015.09.002

Abstract

Abstract: Objective

To study the correct serology identification methods of para-Bombay phenotype and search compatible donors for rare blood type.

Methods

A total of 4 cases of positive and reverse typing discrepancy were identified comprehensively. ABO positive and reverse typing, Lewis blood type identification, H antigen detection, red blood cell absorption-elution test, cold antibody detection and hemagglutination inhibition test for blood type substance in saliva were performed. A family investigation was made.

Results

All the 4 cases were confirmed as para-Bombay phenotype. Proband c's sister was also proved that she was the same para-Bombay phenotype.

Conclusions

The cases of positive and reverse typing discrepancy should be added other essential tests for para-Bombay phenotype. The detection of cold antibody assists in not only identifying para-Bombay phenotype but also selecting compatible blood for transfusion. Family investigation makes possible observe source and inheritance of para-Bombay phenotype and provide homogeneous donors for transfusion.

Key words: Para-Bombay phenotype, ABD positive and reverse typing, H antigen, Cold antibody

CLC Number:

R446.11

ZHU Zehang, LU Yuanshan. Study on the serology identification of para-Bombay phenotype and the investigation of a family[J]. Laboratory Medicine, 2015, 30(9): 874-876.

Figures/Tables 3

References 11

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被检者	RBC与抗体试剂反应					血清与试剂红细胞反应
被检者	抗-A	抗-B	抗-H	抗Le^a	抗Le^b	Ac	Bc	Oc	自身c
a	-	-	-	-	1+^w	2+^s	-	±	-
b	-	-	-	-	1+	3+	±	±	-
c	-	-	-	-	1+	4+	1+	2+	-
d	-	-	-	-	1+	1+^w	1+^w	1+^w	-

被检者	RBC与抗体试剂反应					血清与试剂红细胞反应
被检者	抗-A	抗-B	抗-H	抗Le^a	抗Le^b	Ac	Bc	Oc	自身c
a	-	-	-	-	1+^w	2+^s	-	±	-
b	-	-	-	-	1+	3+	±	±	-
c	-	-	-	-	1+	4+	1+	2+	-
d	-	-	-	-	1+	1+^w	1+^w	1+^w	-

被检者	(红细胞+人源抗-A)放散液+Ac	(红细胞+人源抗-B)放散液+Bc	Oc放散液(对照)
a	-	2+	-
b	-	1+	-
c	-	2+	-
d	2+	1+^s	-

被检者	(红细胞+人源抗-A)放散液+Ac	(红细胞+人源抗-B)放散液+Bc	Oc放散液(对照)
a	-	2+	-
b	-	1+	-
c	-	2+	-
d	2+	1+^s	-

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