Research on molecular mechanisms of PMA-induced platelet GPⅠbα shedding
1. Laboratory Center,Shanghai Traditional Chinese Medicine Hospital, Shanghai University of Traditional Chinese Medicine,Shanghai 200071, China; 2. Blood Engineering Laboratory,Shanghai Blood Center,Shanghai 200051, China
[1]Andrews RK,Karunakaran D,Gardiner EE,et al. Platelet receptor proteolysis: a mechanism for downregulating platelet reactivity[J]. Arterioscler Thromb Vasc Biol,2007, 27(7): 1511-1520.[2] Canault M,Duerschmied D,Brill A,et al. p38 mitogen-activated protein kinase activation during platelet storage: consequences for platelet recovery and hemostatic function in vivo[J]. Blood,2010,115(9): 1835-1842.[3] Gardiner EE,Karunakaran D,Shen Y,et al. Controlled shedding of platelet glycoprotein (GP)Ⅵ and GPIb-Ⅸ-Ⅴ by ADAM family metalloproteinases[J]. J Thromb Haemost,2007, 5(7): 1530-1537.[4]王志成,张晓锋,陈晓宇,等. 三苯氧胺诱导血小板凋亡的研究[J]. 安徽医科大学学报,2011, 46(9): 853-857.[5]Wang Y,Herrera AH,Li Y,et al. Regulation of mature ADAM17 by redox agents for L-selectin shedding[J]. J Immunol,2009, 182(4): 2449-2457.[6]Dikalov S. Cross talk between mitochondria and NADPH oxidases[J]. Free Radic Biol Med,2011, 51(7): 1289-1301.[7]Du X. Signaling and regulation of the platelet glycoprotein Ib-Ⅸ-Ⅴ complex[J]. Curr Opin Hematol,2007, 14(3): 262-269.[8]Bergmeier W,Piffath CL,Cheng G,et al. Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo[J]. Circ Res,2004,95(7): 677-683.[9] Gooz M. ADAM-17: the enzyme that does it all[J]. Crit Rev Biochem Mol Biol,2010,45(2): 146-169.[10]Klein T,Bischoff R. Active metalloproteases of A the disintegrin and metalloprotease (ADAM) family: biological function and structure[J]. J Proteome Res,2011, 10(1): 17-33.[11]Xu P,Derynck R. Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation[J]. Mol Cell,2010, 37(4): 551-566.[12]Killock DJ,Ivetic〖KG-*3/4〗' A. The cytoplasmic domains of TNFalpha-converting enzyme (TACE/ADAM17) and L-selectin are regulated differently by p38 MAPK and PKC to promote ectodomain shedding[J]. Biochem J,2010, 428(2): 293-304.[13]Horiuchi K,Le Gall S,Schulte M,et al. Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx[J]. Mol Biol Cell,2007, 18(1):176-188.[14]陈宁,傅毅,应雅韵,等. NAD(P)H氧化酶p22phox亚基C242T基因多态性与脑梗死的关系[J]. 检验医学,2011, 26(3): 175-179.[15]Brill A,Chauhan AK,Canault M,et al. Oxidative stress activates ADAM17/TACE and induces its target receptor shedding in platelets in a p38-dependent fashion[J]. Cardiovasc Res,2009, 84(1): 137-144.[16]Wang Z,Shi Q,Yan R,et al. The role of calpain in the regulation of ADAM17-dependent GPIbalpha ectodomain shedding[J]. Arch Biochem Biophys,2010, 495(2): 136-143.