RANTES和Eotaxin与结核病

doi:10.3969/j.issn.1673-8640.2015.10.020

检验医学 ›› 2015, Vol. 30 ›› Issue (10): 1048-1052.DOI: 10.3969/j.issn.1673-8640.2015.10.020

RANTES和Eotaxin与结核病

赵琰枫¹, 冯晓燕², 张贺秋¹

1. 温州医科大学,浙江温州 325035
2. 军事医学科学院基础医学研究所,北京 100850

收稿日期:2014-12-19 出版日期:2015-10-30 发布日期:2015-11-04
作者简介:null
作者简介:赵琰枫,女,1989年生,硕士,主要从事病原生物学研究。

通讯作者:张贺秋,联系电话:010-66932304。
基金资助:
国家863计划资助项目(2011AA02A113)

RANTES and eotaxin in tuberculosis

ZHAO Yanfeng¹, FENG Xiaoyan², ZHANG Heqiu¹

1 .Wenzhou Medical University, Zhejiang Wenzhou 325035, China
2. Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, China

Received:2014-12-19 Online:2015-10-30 Published:2015-11-04

摘要/Abstract

摘要：

结核病仍然是困扰人类健康的常见传染病之一。我国是22个结核病高负担国家之一,早期准确的诊断以及及时有效的治疗对于控制结核病流行是必不可少的。结核病传统的实验室诊断方法存在许多不足之处,新的诊断方法由于没有良好的生物标志物而受到了限制。随着国内外对调节活化正常T细胞表达与分泌趋化因子(RANTES)及嗜酸细胞活化趋化因子(Eotaxin)研究的日益增多,越来越多的研究显示,RANTES及Eotaxin对于结核病具有潜在的诊断和监测价值。

关键词: 调节活化正常T细胞表达与分泌趋化因子, 嗜酸细胞活化趋化因子, 结核病

Abstract:

Tuberculosis remains one of the most common infectious diseases to threat human health. China is the 22nd high tuberculosis burden country. Early correct diagnosis and proper treatment are critical to control Mycobacterium tuberculosis infection. The traditional laboratory diagnosis methods of tuberculosis have many shortcomings, and no excellent biomarkers are found and verified,which hampers and attempts to develop new tests. Along with the increasing research of regulated upon activation normal T cell expressed and secreted(RANTES) and eotaxin, more and more studies indicate that RANTES and eotaxin have potential significance in the diagnosis and monitoring of tuberculosis.

Key words: Regulated upon activation normal T cell expressed and secreted, Eotaxin, Tuberculosis

中图分类号:

R446.5

赵琰枫, 冯晓燕, 张贺秋. RANTES和Eotaxin与结核病[J]. 检验医学, 2015, 30(10): 1048-1052.

ZHAO Yanfeng, FENG Xiaoyan, ZHANG Heqiu. RANTES and eotaxin in tuberculosis[J]. Laboratory Medicine, 2015, 30(10): 1048-1052.

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RANTES和Eotaxin与结核病

RANTES and eotaxin in tuberculosis

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