检验医学 ›› 2013, Vol. 28 ›› Issue (4): 287-289.DOI: 10.3969/j.issn.1673-8640.2013.04.008

• 临床应用研究.论著 • 上一篇    下一篇

复发性阴道炎的病原学研究

岳文燕1,单江静2   

  1. 1. 绍兴文理学院医学院,浙江 绍兴 312000;2. 绍兴市人民医院,浙江 绍兴 312000
  • 收稿日期:2013-01-15 修回日期:2012-11-30 出版日期:2013-04-30 发布日期:2013-04-05
  • 作者简介:岳文燕,女,1980年生,硕士,讲师,主要从事病原生物学检验教学与研究工作。

Pathogenic analysis of recurrent vaginitis

  1. 1. Medical School of Shaoxing University,Zhejiang Shaoxing 312000,China;2. Shaoxing People′s Hospital, Zhejiang Shaoxing 312000,China
  • Received:2013-01-15 Revised:2012-11-30 Online:2013-04-30 Published:2013-04-05

摘要: 目的 了解复发性阴道炎患者阴道分泌物病原体种类及分布,为临床诊治提供科学的参考依据。 方法 采集妇科门诊就诊的阴道炎患者的阴道分泌物,用生理盐水涂片法检测阴道毛滴虫,快速革兰染色法检测假丝酵母,唾液酸酶法进行细菌性阴道病(BV)的快速检测。 结果 67例复发患者共检出病原体32例(47.76%),单纯病原体感染19例(28.36%),其中单纯假丝酵母10例(14.93%),单纯滴虫感染1例(1.49%),单纯BV阳性8例(11.94%);病原体混合感染13例(19.40%),其中假丝酵母合并BV阳性10例(14.93%),滴虫合并BV阳性2例(2.99%),滴虫合并假丝酵母和BV阳性1例(1.49%)。123例对照组患者共检出病原体50例(40.65%),包括单纯病原体感染40例(32.52%),其中单纯假丝酵母18例(14.63%),单纯滴虫感染2例(1.63%),单纯BV阳性20例(16.26%);病原体混合感染10例(8.13%),其中假丝酵母合并BV阳性8例(6.50%),滴虫合并BV阳性2例(1.63%)。 结论 复发性阴道炎患者阴道病原体混合感染情况很突出,占检出病原体病例的近半数,尤其是合并细菌感染,应引起临床的重视。

关键词: 阴道炎, 假丝酵母菌, 细菌性阴道病, 阴道毛滴虫

Abstract: Objective To investigate the species and distribution of pathogens in the vaginal secretion of patients with recurrent vaginitis,and to provide reference for clinical application.  Methods The vaginal secretion samples were collected from the outpatients with vaginitis in the Department of Gynecology. The normal saline smear method was used to detect the trichomonas,rapid Gram′s staining was used to detect Candida pelliculosa,and sialidase method was used to detect bacterial vaginosis (BV). Results In 67 patients with recurrent vaginitis,32 cases with pathogen infection were detected(47.76%),and 19 cases with single pathogen infection were detected (28.36%),including 10 cases of single Candida pelliculosa infection (14.93%),1 case of single trichomonas infection (1.49%) and 8 cases of single positive BV (11.94%). A total of 13 cases of mixed infection were detected (19.40%),among which Candida pelliculosa mixing with positive BV had 10 cases (14.93%),trichomonas mixing with positive BV had 2 cases (2.99%), and Candida pelliculosa and trichomonas mixing with positive BV had 1 case (1.49%). In 123 cases of control group,50 cases were found with pathogen infection (40.65%), including 40 single infection cases(32.52%) and 10 mixed infection cases(8.13%). Among the 40 single infection cases,single Candida pelliculosa infection was found in 18 cases(14.63%),single trichomonas infection was found in 2 cases (1.63%),and single positive BV was found in 20 cases(16.26%). Among the 10 mixed infection cases,Candida pelliculosa mixing with positive BV had 8 cases (6.50%),and trichomonas mixing with positive BV had 2 cases (1.63%). Conclusions The pathogen mixed infection in patients with recurrent vaginitis is notable,accounting for nearly half of the detected pathogens,especially the cases mixing with BV,and it should arouse the notice in clinical application.

Key words: Vaginitis, Candida pelliculosa, Bacterial vaginosis, Trichomonas