Abstract:

Objective To investigate the main causes for false increasing of white blood cells and small round epithelial cells determined by UF-1000i urine sediment analyzer. Methods Urine samples of outpatients were collected. UF-1000i urine sediment analyzer and microscopy were used,and the results of these 2 methods were compared. The main causes for false increasing of white blood cells and small round epithelial cells were evaluated. Results The false positive rate of white blood cells determined by UF-1000i urine sediment analyzer was 12.58%,mainly due to small round epithelial cells（69.6%）,bacteria（12.8%）,flat epithelial cells（8.0%） and fat droplets（6.4%）. The false positive rate of small round epithelial cells was 4.6%,mainly due to leukocytes（67.9%）,fat droplets（15.5%） and trichomoniasis（11.9%）. Conclusions When the urine pathological components increase,a variety of factors can affect UF-1000i urine sediment analyzer's determination results on white blood cells and small round epithelial cells,and false positivity appears. The application of UF-1000i urine sediment analyzer can only be a determination as a preliminary screening method,and microscopy is still be gold standard for urine sediment analysis.

Key words: UF-1000i urine sediment analyzer, False increasing, White blood cell, Small round epithelial cell, Microscopy