Abstract:

Objective To investigate the infection rate of eperythrozoon in patients with blood diseases. Methods A total of 50 healthy subjects and 223 patients with blood diseases were enrolled. Eperythrozoon was determined by acridine staining. The patients with blood diseases were classified according to disease types and characteristics. The relationship between infection rate and blood diseases was analyzed. Results The infection rates in healthy subject group and blood disease group by acridine staining were 12.00% and 28.25%,respectively. The infection rate in blood disease group was higher than that in healthy subject group. No difference of infection rate was found between males and females（P>0.05）. People from 45 to 65 years old had the highest infection rate,and the infection rates showed no statistical significance for ages（P>0.05）. The infection rates between outpatients from hematology department and inpatients had no statistical significance（P>0.05）. The infection rate of patients with lymphoma was the highest in blood disease group. There was statistical significance for the infection rate between patients with lymphoma and patients with other blood diseases（P<0.05）. There was no statistical significance between patients with acute myeloid leukemia and patients with acute lymphocyte leukemia（P>0.05）. Conclusions Eperythrozoon mostly infects people from 45 to 65 years old,and there is no difference between males and females. Nosocomial infection is less likely to occur. Patients with blood diseases especially with lymphoma are more susceptible than healthy subjects to eperythrozoon. Different types of blood diseases have different infection rates. Thus,attention should be paid during treatment.

Key words: Human eperythrozoon, Acridine staining, Blood diseases