doi:10.3969/j.issn.1673-8640.2015.05.026

Abstract

CLC Number:

R446.11

Figures/Tables 3

References 12

[1]	VINCENT JL.Clinical sepsis and septic Shock-definition, diagnosis and management principles[J]. Langenbecks Arch Surg,2008,393(6):817-824.
[2]	LEIBOVICI L, GREENSHTAIN S, COHEN O, et al.Bacteremia in febrile patients. A clinical model for diagnosis[J]. Arch Intern Med,1991,151(9):1801-1806.
[3]	DELLINGER RP, LEVY MM, CARLET JM, et al.Surviving Sepsis Campaign:international guidelines for management of severe sepsis and septic shock[J]. Intensive Care Med,2008,34(1):17-60.
[4]	LEVY MM, DELLINGER RP, TOWNSEND SR, et al.The Surviving Sepsis Campaign:results of an international guidelinebased performance improvement program targeting severe sepsis[J]. Intensive Care Med,2010,36(2):222-231.
[5]	NUUTILA J, LILIUS EM.Distinction between bacterial and viral infections[J]. Curr Opin Inect Dis,2007,20(3):304-310.
[6]	LUTFIYYA MN, HENLEY E, CHANG LF, et al.Diagnosis and treatment of community-acquired pneumonia[J]. Am Fam Physician,2006,73(3):442-450.
[7]	ZAHOREC. Ratio of neutrophil to lymphocyte counts-rapid and simple parameter of systemic inflammation and stress in critically ill[J]. Bratisl Lek Listy,2001,102(1):5-14.
[8]	CORNELIS PC, PAUL TL, REJIV B, et al.Lymphocyopenia and neutrophil-lymphocte count ratio predict bacteremia better than conventional infection markers in an emergency care unit[J]. Critical Care,2010,14(5):R192.
[9]	蒋燕, 巨容. 新生儿败血症患者血小板变化的临床意义[J]. 川北医学院学报,2012,27(5):496-499.
[10]	SHARMA R, TEPAS JJ, HUDAK ML, et al.Neonatal gut barrier and multiple organ failure:role of endotoxin and proinflammatory cytokines in sepsis and necrotizing enterocolitis[J]. J Pedia Surg,2007,42(3):454-461.
[11]	SMITH RA, BOSONNET L, RARATY M, et al.Preoperative platelet-lymphocyte ratio is an independent significant prognostic marker in resected pancreatic ductal adenocarcinoma[J]. Am J Surg,2009,197(4):466-472.
[12]	侯伟伟,肖倩茹,江涟,等. 血清降钙素原作为菌血症预示因子临床价值的研究[J].检验医学, 2014,29(8):802-805.

组别	WBC (×10⁹/L)	NEU (×10⁹/L)	NLR	PLT (×10⁹/L)	CRP (mg/L)	PCT (ng/mL)	LYM (×10⁹/L)	PLR
BSI组	10.93(9.50)	9.28(9.94)	14.22(17.12)	180.60±81.90	115.00(133.50)	2.56(18.99)	0.77(0.57)	201.69(235.96)
对照组	8.10(6.33)	6.04(5.30)	7.08(6.54)	217.60±116.50	57.30(50.00)	0.05(0.03)	0.93(0.82)	201.50(200.41)
统计值	Z=-2.705	Z=-3.036	Z=-3.471	t=2.049	Z=-4.037	Z=0.000	Z=-1.623	Z=-0.352
P值	0.007	0.002	0.001	0.043	0.000	0.000	0.105	0.725

组别	WBC (×10⁹/L)	NEU (×10⁹/L)	NLR	PLT (×10⁹/L)	CRP (mg/L)	PCT (ng/mL)	LYM (×10⁹/L)	PLR
BSI组	10.93(9.50)	9.28(9.94)	14.22(17.12)	180.60±81.90	115.00(133.50)	2.56(18.99)	0.77(0.57)	201.69(235.96)
对照组	8.10(6.33)	6.04(5.30)	7.08(6.54)	217.60±116.50	57.30(50.00)	0.05(0.03)	0.93(0.82)	201.50(200.41)
统计值	Z=-2.705	Z=-3.036	Z=-3.471	t=2.049	Z=-4.037	Z=0.000	Z=-1.623	Z=-0.352
P值	0.007	0.002	0.001	0.043	0.000	0.000	0.105	0.725

项目	截断值	敏感性(%)	特异性(%)	阳性预测值(%)	阴性预测值(%)	AUC
WBC	>12.0×10⁹/L	42.67	80.43	78.05	46.25	0.65
NEU	>9.0×10⁹/L	52.00	76.09	75.61	45.00	0.67
NLR	>11.5	58.67	76.09	81.13	52.94	0.69
PLT	<160×10⁹/L	44.00	67.39	68.75	42.47	0.58
CRP	>60 mg/L	72.00	52.17	72.00	54.35	0.72
PCT	>0.5 ng/mL	85.33	93.48	95.52	79.25	0.89

项目	截断值	敏感性(%)	特异性(%)	阳性预测值(%)	阴性预测值(%)	AUC
WBC	>12.0×10⁹/L	42.67	80.43	78.05	46.25	0.65
NEU	>9.0×10⁹/L	52.00	76.09	75.61	45.00	0.67
NLR	>11.5	58.67	76.09	81.13	52.94	0.69
PLT	<160×10⁹/L	44.00	67.39	68.75	42.47	0.58
CRP	>60 mg/L	72.00	52.17	72.00	54.35	0.72
PCT	>0.5 ng/mL	85.33	93.48	95.52	79.25	0.89

[1]	DENG Chenxia, MEI Yanping, ZHANG Xia, HUANG Baoshan, TIAN Dan, CAO Mengting, HU Yongqi, LIN Yongping, TIAN Lijun. Depolymerization effect of optical platelet count on reversible platelet aggregation after blood collection [J]. Laboratory Medicine, 2023, 38(11): 1087-1090.
[2]	LU Tingyan, GU Danfeng, WANG Yahong, GE Yafang, YANG Haiou. Evaluation of vaginal secretion routine determination modes and review criteria analysis [J]. Laboratory Medicine, 2023, 38(11): 1091-1097.
[3]	. [J]. Laboratory Medicine, 2023, 38(11): 1098-1100.
[4]	. [J]. Laboratory Medicine, 2023, 38(10): 983-986.
[5]	. [J]. Laboratory Medicine, 2023, 38(9): 901-904.
[6]	. [J]. Laboratory Medicine, 2023, 38(9): 905-908.
[7]	CHENG Xu, YANG Cunqing, PANG Bo, GU Chun, HOU Xueyun, FEI Jiaxin, WU Min, LI Jun, LIU Guijian. Number and activity of peripheral blood eosinophils in obese people [J]. Laboratory Medicine, 2023, 38(9): 855-859.
[8]	LEI Jing, MAN Qiuhong, ZHAO Renjia, ZHANG Tiejun, JIANG Yanfeng, XU Kelin, SUO Chen, CHEN Xingdong. Elevated red blood cell distribution width increasing the risk of heart failure：a cohort study based on the UK Biobank [J]. Laboratory Medicine, 2023, 38(9): 860-864.
[9]	DUAN Lili, JIANG Chang, ZHOU Dongmei. Role of PLR in ankylosing spondylitis patients with positive antinuclear antibody [J]. Laboratory Medicine, 2023, 38(7): 669-674.
[10]	XIA Yanyan, XIA Yongquan, SONG Guanghao, XIA Mao. Role of coagulation-related monitoring indicators in the course of rivaroxaban anticoagulation for acute venous thromboembolism in elderly patients [J]. Laboratory Medicine, 2023, 38(5): 475-478.
[11]	CHEN Yi, WANG Jia, XU Zhiwei, ZHAI Yaping, XUAN Weixia. Effects of different anticoagulants on phagocytosis，activation and apoptosis of in vitro neutrophil function [J]. Laboratory Medicine, 2023, 38(5): 479-483.
[12]	YANG Liyuan, DAI Wanqin, WANG Xiaotong, LOU Xiaoli, WANG Yue, HOU Yanqiang. Effect of peripheral blood neutrophils on interferon-gamma release assay of Mycobacterium tuberculosis [J]. Laboratory Medicine, 2023, 38(5): 484-488.
[13]	. [J]. Laboratory Medicine, 2023, 38(5): 502-504.
[14]	. [J]. Laboratory Medicine, 2023, 38(1): 69-72.
[15]	XIE Yuan, YI Wanwan, SHI Qiuyuan, LÜ Zhongwei, LIU Jin. Clinical value of thromboelastography and conventional coagulation tests in evaluating coagulation status of colon cancer and colon polyps [J]. Laboratory Medicine, 2022, 37(11): 1007-1011.

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

Figures/Tables 3

References 12

Related Articles 15

Recommended Articles

Metrics