Abstract:

Objective　To provide the reference for the reasonable supplement and its study of trace element levels by investigating the distribution and variation regularity of Cu, Ca, Mg, Zn and Fe of children in Panyu district, Guangzhou city. Methods　Five trace elements(Cu, Ca, Mg, Zn and Fe) in whole blood of 3 476 children were detected by atomic absorption spectrometer. The children were classified into 5 age groups：infancy group (112 months old, 743 cases), toddler age group (>12 years old, 916 cases), preschool age group (36 years old, 988 cases)，school age group(711 years old, 579 cases) and adolescence group(1218 years old, 250 cases). Based on sex, each group was subclassified into female and male groups. The levels of the 5 trace elements were analyzed among different sex and age groups. Results　The abnormal rates of Cu and Mg were low. The total deficiency rates were 1.5% and 0.26%，and the total exceeding standard rates were 0.08% and 0.06%.It was common for the deficiency of Zn and Fe, and their total deficiency rates was 21.0% and 19.7%，and with the increasing of age, their deficiency rates were downward. The total exceeding standard rates of Zn and Fe were 1.8% and 0%.The total deficiency rate of Ca was 6.7%，and with the increasing of age, the deficiency rate was upward. The total exceeding standard rate of Ca was 1.9%. In preschool age and adolescence groups, the levels of Mg and Fe had statistical significance between males and females （t＝2.563, 2.172, 2.822 and 4.537, P<0.01）. The levels of the other trace elements had no statistical significance between males and females in each age group（P>0.05）. The levels of Zn and Fe were upward with the increasing of age, and the levels of Cu and Ca were downward. The level of Mg was stable. Conclusions　The abnormal rates of Zn, Fe and Ca in whole blood of children in Panyu district are high. The distributions of Cu and Mg become reasonable. The clinical guidance and research of Zn，Fe and Ca should be strengthened.

Key words: Trace element, Whole blood, Child, Atomic absorption spectrometer