Laboratory Medicine ›› 2025, Vol. 40 ›› Issue (3): 218-222.DOI: 10.3969/j.issn.1673-8640.2025.03.003

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Autoimmune liver disease in children and progress of laboratory diagnosis

MA Zhan, WENG Wenhao   

  1. Department of Clinical Laboratory,Shanghai Children's Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200062,China
  • Received:2024-07-19 Revised:2024-11-05 Online:2025-03-30 Published:2025-04-10

Abstract:

Autoimmune liver diseases(ALD) is a group of chronic progressive inflammation of liver caused by immune dysfunction. In the recent years,the incidence of ALD in children has risen significantly. The occurrence,clinical characteristics and laboratory diagnosis of ALD in children differ notably from those in adults. This review focuses on the classification and characteristics of common ALD in children,the status and development in laboratory diagnosis,unresolved challenges and genetic susceptibility. The aim is to provide a reference for clinical research and to improve the diagnosis and treatment of ALD in children.

Key words: Autoimmune liver disease, Children, Clinical laboratory diagnosis

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