Laboratory Medicine ›› 2015, Vol. 30 ›› Issue (6): 567-570.DOI: 10.3969/j.issn.1673-8640.2015.06.005

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Comparison on in vitro antibacterial activities for five kinds of trditional Chinese medicine granules and decoctions against five kinds of clinical drug-resistant strains

LI Aiwen, TAN Junqing, WANG Kangchun, HUANG Shuangwang, ZHOU Bing, LIU Qibo   

  1. Department of Clinical Laboratory, the Second Traditional Chinese Medicine Hospital of Guangdong, Guangdong Guangzhou 510095, China
  • Received:2015-01-15 Online:2015-06-30 Published:2015-07-03

Abstract: Objective

To compare in vitro antibacterial activities for 5 kinds of traditional Chinese medicine granules and decoctions (Baicalin, Forsythia, Mint, Dandelion and Sophora) against 5 kinds of clinical drug-resistant strains.

Methods

According to the related researches on traditional Chinese medicine against resistant bacteria, 5 kinds of traditional Chinese medicine granules and decoctions were selected, and 5 kinds of clinical drug-resistant strains from blood plate were collected. They included meticillin-resistant Staphylococcus aureus (MRSA), Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae and Acinetobacter baumannii. The disc agar diffusion method was used, and the diameter of bacteriostatic ring was measured. The bacteriostatic effects were analyzed statistically.

Results

Five traditional Chinese medicines showed different antibacterial activities, with Baicalin being the most potent. The same kind of traditional Chinese medicine granule and decoction was compared. For MRSA, Baicalin, Forsythia, Mint, Dandelion and Sophora had antibacterial effects, and there was no statistical significance (P>0.05). For Pseudomonas aeruginosa and Acinetobacter baumannii, Baicalin, Forsythia and Mint had antibacterial effects, and there was no statistical significance (P>0.05). For Escherichia coli and Klebsiella pneumoniae, Baicalin had antibacterial effects, and there was no statistical significance (P>0.05).

Conclusions

The same concentrations of Baicalin, Forsythia, Mint, Dandelion and Sophora decoctions have not obvious difference for antibacterial effect.

Key words: Traditional Chinese medicine granule, Traditional Chinese medicine decoction, Bacteriostatic ring, Clinical drug-resistant strain

CLC Number: