Advantages and pathogenicity of Enterococci

doi:10.3969/j.issn.1673-8640.2023.11.018

Abstract

Abstract:

Enterococci are Gram-positive facultative anaerobic cocci，mainly distributed in the intestine，less in vagina or oral cavity. In this genus，Enterococcus faecalis and Enterococcus faecium are the most common species. Enterococci，as commensal bacteria，colonize in the digestive system of humans and animals participating the regulation of immune. Enterococcus has been used as a probiotic food additive，or as an adjunct to the treatment of intestinal dysbiosis. Recently，the use of Enterococcus as probiotics may lead to the occurrence of virulence and multidrug resistance of the genus，which may lead to clinical infection. Therefore，Enterococcus is also regarded as a conditional pathogen. Variation of Enterococci is positively associated with nosocomial infection. Enterococci have the ability to transfer from the gastrointestinal tract to various tissues and organs，and their virulence and drug resistance are risk factors that affect the treatment of infection. A large number of studies on the plasticity of Enterococcus genome predict that the commensal bacteria may mutate into pathogenic bacteria. This review aims to discuss the beneficial properties of Enterococci and pathogenicity.

Key words: Enterococcus, Probiotics, Vancomycin resistance, Opportunistic pathogen

CLC Number:

R378.1

TIAN Yuanyuan, JIA Xiongfei. Advantages and pathogenicity of Enterococci[J]. Laboratory Medicine, 2023, 38(11): 1101-1105.

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