液相色谱-串联质谱法监测血清茶碱浓度及室间质量评价
Liquid chromatography-tandem mass spectrometry for the monitoring of theophylline concentration in serum and its application to external quality assessment
液相色谱-串联质谱法监测血清茶碱浓度及室间质量评价 |
|
孙旭颖 |
Liquid chromatography-tandem mass spectrometry for the monitoring of theophylline concentration in serum and its application to external quality assessment |
| 图2 茶碱和茶碱-D6内标的碎片离子图注:在正离子扫描模式下,茶碱主要形成[M+H] + mz 181.0分子离子,选择性对分子离子峰碎裂后的二级质谱分析,主要形成mz 124.0、mz 96.2和mz 69.3的碎片离子;内标茶碱-D6的质谱行为与茶碱相似,形成mz 187.0的分子离子,碎裂后的二级质谱图形成mz 127.0、mz 99.1和mz 72.0的碎片离子 |
| |