常用药物对实验室检测项目测定结果的影响

doi:10.3969/j.issn.1673-8640.2019.11.017

检验医学 ›› 2019, Vol. 34 ›› Issue (11): 1038-1044.DOI: 10.3969/j.issn.1673-8640.2019.11.017

常用药物对实验室检测项目测定结果的影响

朱宇清, 赵晓君, 陈子齐, 王华梁

上海市临床检验中心,上海 200126

收稿日期:2019-02-27 出版日期:2019-11-30 发布日期:2019-12-05
作者简介:null
作者简介：朱宇清,女,1967年生,硕士,主任技师,主要从事免疫学检验及质量控制研究。

Influence of common drugs on clinical test results

ZHU Yuqing, ZHAO Xiaojun, CHEN Ziqi, WANG Hualiang

Shanghai Center for Clinical Laboratory,Shanghai 200126,China

Received:2019-02-27 Online:2019-11-30 Published:2019-12-05

摘要/Abstract

摘要：

文章阐述了常用药物对临床检验结果的影响机制,包括药物本身及代谢产物对待测物的影响,如药物本身的药理作用、药物的生物亲和作用、药物的代谢及代谢产物对待测物排泄的影响等;介绍了常用药物,包括抗菌药物、心血管系统药物、解热镇痛类药物、维生素、激素类药物、抗肿瘤药物、糖尿病治疗药物、抗甲状腺药物、精神类药物及其他药物等对各项指标检测结果的影响;最后对如何降低药物对检测结果的影响作了总结,包括与临床医师进行及时有效的沟通、不断改进检验方法等。

关键词: 常用药物, 检验结果, 影响机制

Abstract:

This review focuses on the influence mechanism of common drugs on clinical test results,including the in vivo effect of drugs and metabolites,for example,pharmacological effects,bio-affinity effects,drug metabolism and the influence of metabolites. The influence of common drugs,including antibiotics,cardiovascular drugs,antipyretic analgesics,vitamins,hormone drugs,anti-cancer drugs,diabetes drugs,antithyroid drugs,psychotropic drugs,on clinical test results were introduced. This review finally summarizes the ways on reducing the effect of drugs on clinical test results,including timely and effective communication with clinicians and continuous improvement of clinical test methods.

Key words: Common drugs, Clinical test results, Influence mechanism

中图分类号:

R446.1

朱宇清, 赵晓君, 陈子齐, 王华梁. 常用药物对实验室检测项目测定结果的影响[J]. 检验医学, 2019, 34(11): 1038-1044.

ZHU Yuqing, ZHAO Xiaojun, CHEN Ziqi, WANG Hualiang. Influence of common drugs on clinical test results[J]. Laboratory Medicine, 2019, 34(11): 1038-1044.

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常用药物对实验室检测项目测定结果的影响

Influence of common drugs on clinical test results

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